Supporting people in hospitals across South Australia through vital health and medical research and improved patient care.
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THRF adopts extremely high transparency standards when reporting our financials.
Supports research into the detection, management & treatment of breast cancer.
Funding research into prostate cancer prevention, detection & treatment.
Improving heart health through advances in knowledge & research to beat heart disease.
Our aim is to reduce & eliminate the high incidence of chronic kidney disease and diabetes.
Supports health and wellbeing research & programs for veterans, emergency service personnel and their families.
Driving collaboration, innovation & research to develop best-practice arts, design & health programs.
Supporting world-class stroke research to improve prevention, diagnosis & acute treatment to cure stroke.
Biome Bank is Australia’s first public stool bank, established to treat debilitating bowel conditions and foster research into gut health.
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Did you know, every day in Australia approximately 50 people are diagnosed with breast cancer?
Thanks to lifesaving research, incredible treatment advances continue to be made and breast cancer survival rates are now at an amazing 98 per cent when the cancer remains in the breast.
Sadly, nine people do lose their battle to breast cancer every day. But there is hope for these women.
Associate Professor Claudine Bonder, Professor Angel Lopez and their teams at the Centre for Cancer Biology are leading lifesaving research to stop the growth and spread of the most aggressive breast cancer.
“For the last few years, we’ve been working on the most difficult breast cancer to treat, triple negative breast cancer. This breast cancer is the most aggressive and invasive, which means the cancer cells can quickly access blood vessels as a highway to spread around the body,” A/Prof Bonder said.
We’ve identified a blood hormone that helps breast cancer to grow and spread using blood vessels and have promising data to suggest that this could act as a good target for a new treatment.
While other breast cancer types currently have a targeted treatment, for patients diagnosed with triple negative breast cancer, chemotherapy proves to be the only option.
“Breast cancer can only grow to a certain size before it needs access to the blood supply for nutrients and oxygen. To attract a blood supply, cancer cells can either send out a chemical signal to draw in neighbouring blood vessels (a process called angiogenesis) or build their own blood vessel-like structures and create their own supply (vasculogenic mimicry).
What we’ve shown is this blood hormone supports both processes, helping aggressive breast cancers to grow and spread around a patient’s body. Our theory is that if we can block the function of this hormone we can block the two ways which assist in the growth and spread of aggressive breast cancer.
Now with this exciting knowledge, A/Prof Bonder, Prof Lopez and their teams are hopeful their discovery could lead to a new treatment for the most aggressive breast cancer affecting your community. That wouldn’t be possible without your generous support.
“At the moment these patient’s only treatment option is chemotherapy so our research could lead to an alternative treatment or combine a new therapy with a lower dose of chemotherapy.
“By understanding how this blood hormone contributes to breast cancer growth, we hope to identify a distinct subgroup of breast cancer patients, diagnose them earlier and one day come up with a specific or personalised treatment for them.
“We’re hopeful in the next year we’ll have some really solid evidence which will be what we need to work towards clinical trials.”
Support more lifesaving research like A/Prof Bonder’s today.
Whilst estrogen receptor positive breast cancer has a targeted treatment strategy, many patients develop resistance, leaving them with no option other than chemotherapy. Now these women have hope! read more
It was a pain in her right breast, like that of a torn muscle, which led young mother Kate Shields to a breast cancer diagnosis that she never saw coming. In January last year the 38-year-old mother was diagnosed with aggressive hormonal breast cancer. read more
Always fit and healthy, 56-year-old Deb Holsman never thought she would be diagnosed with breast cancer, let alone one of the most heartbreaking forms of the disease. read more
The Breast Cancer Research Unit at the Basil Hetzel Institute for Translational Health Research (BHI) are determined to develop a new immunotherapy treatment to target breast cancer and other heartbreaking cancers affecting our community. read more
Thanks to your generous support, each year The Hospital Research Foundation (THRF) funds travel grants to support researchers and students to attend various conferences and meetings relevant to their field of research, having the opportunity to network with fellow researchers around the globe. read more
Head of the Cell Signalling Laboratory at the Centre for Cancer Biology (CCB), Associate Professor Yeesim Khew-Goodall is leading a crucial research project focused on overcoming resistance to cancer therapy, particularly in triple negative breast cancer. read more
Can you imagine being diagnosed with a type of cancer that has no targeted treatments? This could change thanks to researchers at the Basil Hetzel Institute for Translational Health Research (BHI) who are working hard to investigate possible treatments for triple negative breast cancer. read more
World-first research is underway at the Basil Hetzel Institute for Translational Health Research (BHI) focusing on using our own immune system to fight solid cancers such as breast cancer with potential for other cancers. read more
Thanks to the incredible generosity of one of our very special donors, Dr Margaret Elcombe, our researchers have been awarded the Elcombe Pre-Clinical Project Grant to pursue a promising new treatment avenue for breast cancer that has spread which if successful would be far less toxic than current treatments. read more